Orthopaedic Basic Science: Foundations of Clinical Practice, 3rd Edition

Orthopaedic basic science 3By

  • Thomas A. Einhorn, MD, Professor and Chairman, Department of Orthopaedic Surgery, Boston University Medical Center, Boston, Massachusetts
  • Regis J. O’Keefe, MD, PhD, Professor of Orthopaedics, Director, Center for Musculoskeletal Research, University of Rochester, Rochester, New York
  • Joseph A. Buckwalter, MD, MS, Professor, Head, and Arthur Steindler Chair, Department of Orthopaedics and Rehabilitation, University of Iowa, Iowa City, Iowa

Advanced technologies for the diagnosis and treatment of musculoskeletal injuries and conditions have changed the way orthopaedic surgeons care for patients. New discoveries about the biology and biomechanics of the musculoskeletal system and the development of more sophisticated tools for probing its many mysteries provide clinicians and scientists with unique opportunities to advance orthopaedic care.

This third edition of Orthopaedic Basic Science: Foundations of Clinical Practice presents orthopaedic surgeons with the foundations of knowledge required to apply advances in scientific discovery to the decisions they will make in the clinic and operating room. Because of the explosion of knowledge in the fields of musculoskeletal science and medicine, the editors and authors have worked to present this information in a format that is comprehensive yet clinically relevant. To accomplish this, the book is divided into three sections so that the reader can follow a hierarchy of knowledge beginning with an understanding of the basic principles of cell and molecular biology, the genetic basis of orthopaedic disease, the fundamentals of skeletal mechanics, and the science supporting the applications of the biomaterials used in orthopaedic procedures. This is followed by updates on the current knowledge of the physiology of individual musculoskeletal tissues and the way diseases and injuries affect those tissues. In addition, because the multitude of scientific developments now require orthopaedic surgeons to critically evaluate new information in order to determine its potential role in our clinical practices, a chapter has been provided on evidence-based orthopaedics and the issues surrounding research design, analysis, and its critical appraisal.

Preparing for Primary Certification or for the Maintenance of Certification (MOC) exam? Orthopaedic Basic Science: Foundations of Clinical Practice explains and reviews the basic science you need to know for your exam.

New to this Edition:

  • Chapter on Evidence Based Medicine.
  • Chapter on Metabolic Bone Diseases.
  • A collection of topic correlated case studies that will be accessible on the web only.


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